61
512
strains housed
2200
fxed embryos provided
585000
live embryos provided
120
adult zebrafsh provided
9
new transgenics or mutant lines obtai-
ned
10
gene knock-down by morpholino
injection
5
training for zebrafsh techniques, bree-
ding and care
Examples of publications including
results partly obtained thanks to the
GIGA-Zebrafish platform
Detry B, Erpicum C, Paupert J, Blacher S,
Maillard C, Bruyere F, Pendeville H, Remacle
T, Lambert V, Balsat C, Ormenese S, Lamaye
F, Janssens E, Moons L, Cataldo D, Kridelka F,
Carmeliet P, Thiry M, Foidart JM, Struman I,
Noel A. Matrix metalloproteinase-2 governs
lymphatic vessel formation as an interstitial
collagenase. Blood 2012;119:5048-56.
Laudadio I, Manfroid I, Achouri Y, Schmidt
D, Wilson MD, Cordi S, Thorrez L, Knoops
L, Jacquemin P, Schuit F, Pierreux CE, Odom
DT, Peers B, Lemaigre FP. A feedback loop
between the liver-enriched transcription
factor network and mir-122 controls hepa-
tocyte diferentiation. Gastroenterology
2012;142:119-29.
Pruvot B, Quiroz Y, Voncken A, Jeanray N, Piot
A, Martial JA, Muller M. A panel of biological
tests reveals developmental efects of phar-
maceutical pollutants on late stage zebrafsh
embryos. Reprod Toxicol 2012;34:568-83.
Soares AR, Reverendo M, Pereira PM, Ni-
velles O, Pendeville H, Bezerra AR, Moura GR,
Struman I, Santos MA. Dre-miR-2188 targets
Nrp2a and mediates proper intersegmental
vessel development in zebrafsh embryos.
PLoS One 2012;7:e39417.
Zebrafsh Facility & Trangenesis
Zebrafsh constitutes an appropriate tool for various uses in Biology. While this model has been used
mainly for the characterization of the development, it is now broadly used as a model for various issues.
The high homology of its genome with the ease of use make it an appropriate model for angiogenesis,
cancer, toxicology for example.
Contact
Marie Winandy
zebrafsh.giga@ulg.ac.be
www.giga.ulg.ac.be/zebra
Services