GIGA - Annual report 2023

research 64 research 65 THESES PhD Brossel Hélène RNA interference of the E3 ubiquitin ligase RAD18 promotes senescence and reduces tumor growth in pleural mesothelioma Cousin François CT thoracique et radiomique : Contribution à la sélection et au suivi des patients traités par inhibiteurs de checkpoint immunitaire Cremer Julie Rôles et mécanismes de régulation de la lipolyse adipocytaire durant la progression tumorale D’aes Tine Investigating the role of a key cell cycle regulator in neuronal death and microglial reactivity after ischemic stroke Deantoni Michele ` Sleep-Wake Regulation in Young and Older Adults: Associations with brain morphology and microstructural integrity Destiné Michel Adapted discrete Legendre transform for denoising and deconvolution of 2D and 3D dynamic radioisotope nephrograms Fudvoye Julie Approche translationnelle des biomarqueurs précoces d’une exposition prénatale et néonatale aux perturbateurs endocriniens Georges Anouk Investigating the development of native and iPSC- derived murine retinae by combining single cell RNA- Seq with ATAC-Seq Gucciardo Fabrice VE-cadherin regulation by uPARAP in lymphatic endothelial cells» Hassoun Zahrat El Oula Ghassan A novel role of EWSR1 protein in RNA translation regulation Joris Thomas Bovine leukemia virus antisense transcription is essential for viral replication and oncogenesis Köse Murat Cem Understanding Disease Progression and Target Identification for Multiple Myeloma Koshmanova Ekaterina Investigating the links between sleep and complex diseases using polygenic risk and ultra-high field MRI Le Bail Romain Microtubule post-translational modifications and their impact on axonal transport Lepiemme Fanny Novel role of early-born oligodendrocyte precursors in cerebral cortex development Lerho Thomas Décrypter les questions non résolues de longue date liées aux infections à alpha/ beta papillomavirus: focus sur la maladie de Bowen et l’adénocarcinome endocervical Mariavelle Emeline Roles of transcription factors in mRNA stability Massoz Laura Unravelling the contribution of ductal progenitors during beta cell regeneration in zebrafish: a focus on calcineurin Moallemian Soodeh Aging and Alzheimer’s Disease: Multimodal Investigation of Image-derived Biomarkers Mortaheb Sepehr Resting Brain and Mind: How brain dynamics are associated with ongoing cognition Requier Florence Investigating the Influence of Meditation on Cognition in the Aging Population Reynders Célia Implication des infections à papillomavirus humains dans la carcinogenèse œsophagienne et endocervicale Sibille Anne Eosinophils in non-small cell lung cancer Tran My Hanh SOBJ Characterizing the biological properties of traditional medicinal plants from northern Vietnam using zebrafish larvae, cell culture and microorganisms Turchetto Silvia Membrane-bound organelles: a new role as self-sustaining machineries Vandermeulen Morgan Mesenchymal Stromal Cells in Liver Transplantation: translational investigations from a phase I-II clinical trial to a rodent model of acute graft rejection Willems Mégane Eosinophils inhibit response to chemotherapy: mechanisms, preclinical and clinical study in mesothelioma

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