GIGA - Annual report 2023

platforms 90 platforms 91 The animal facility recently welcomed a computed tomography (microCT) and a positron emission tomography (microPET), thanks to a funding of 850,000 euros obtained from the “Fondation Belge contre le cancer” (promotor, Pr Nadia Withofs, Pr Roland Hustinx as copromotor, in collaboration with Pr Pierre Drion). This highly powerful equipment will be accessible to all researchers at the University of Liège. The objective is to perform research projects involving preclinical in vivo molecular imaging, not only in oncology, but also in other fields such as inflammation and fibrosis. MicroPET is a nuclear medicine molecular imaging technique. Utilizing a tracer labeled with a positron-emitting isotope (β+ radiation), microPET allows for precise visualization, characterization, and quantification of a biological process of interest non-invasively, with no depth limits in tissue, high sensitivity, and sub-millimeter spatial resolution. MicroCT can be used independently or in combination with microPET, providing localization information and anatomical detail of lesions with a spatial resolution of up to 50 μm. It enables acquisition of CT images of the subject’s entire body at extremely low radiation doses, while maintaining excellent contrast. In 2023 www.gigamousefacility.uliege.be Contact Services Colony management Line cryopreservation Line rederivation and revitalisation Training of people involved with the animals «On-demand» studies x

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