2025 GIGA Annual Report | 31 Coraline Radermecker HER PROJECT Study of the long-term effect of pulmonary marginal neutrophils on the identity, dynamics and functions of pulmonary endothelium. The project aims to investigate how pulmonary marginal neutrophils, short-lived immune cells, influence the heterogeneity and function of pulmonary capillary endothelial cells under conditions of homeostasis and during inflammatory processes. This will improve our understanding of endothelial cell dynamics and heterogeneity, as well as the role played by the neutrophil-endothelial cell axis in the lung. Finally, this project could help identify new therapeutic targets for diseases associated with dysfunction of the vascular system. ABOUT HER Coraline Radermecker has a degree in Veterinary Medicine from the University of Liège. After graduating in 2012, she was quickly drawn to the world of research, a passion that came to the fore when she met Professor Fabrice Bureau, a specialist in Cellular and Molecular Immunology. During her studies, although she initially intended to pursue a career in equine medicine, her curiosity for basic sciences such as physiology, biology and immunology led her to explore the field of research. It was during an internship in Professor Bureau’s laboratory that she discovered a real vocation for scientific research. This experience led her to undertake a PhD in Immunology in the same laboratory. After spending four years working on her doctoral thesis, she joined Professor Thomas Marichal’s Immunophysiology laboratory, where she continued her research. In 2024, she was appointed a qualified researcher by the F.R.S.-FNRS to continue her research on pulmonary neutrophils. Throughout her career, Coraline has combined her passion for basic science and applied research, while making a significant contribution to the advancement of knowledge in immunology and physiology.
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