Christoph Klose leads the "Neuro-immune Interactions" group at Charité Berlin. His group recently identified signaling pathways by which the nervous system regulates innate lymphoid cells (ILCs) and type 2 immune responses via the production of neuropeptides (neuromedin U) and neurotransmitters (norepinephrine).  To systematically investigate neuro-immune crosstalk at mucosal surfaces in health and disease, Christoph's group develops genetic tools allowing experimental manipulation of neurons and ILCs. Combing cutting-edge technologies in the fields of immunology, neuroscience and genomics, they aim to conceptually understand neuro-immune interaction and uncover signaling pathways that could be therapeutically harnessed.